Bioresorbable Scaffolds for PAD: A New Approach to Durability in Peripheral Artery Disease | Chris Hague
MedTech Unboxed: Presented by Chamfr
Why have peripheral artery disease interventions been so difficult to make durable over time? In this episode of MedTech Unboxed, Steve talks with Chris Hague of Ephemeral Medical about the engineering and clinical challenge of building a bioresorbable scaffold specifically for peripheral artery disease rather than adapting a coronary design.
Chris explains why peripheral vessels are harder to treat than coronary arteries, where existing options like balloons and nitinol stents can fall short, and why radial strength, lesion length, vessel motion, and long-term durability all matter in PAD. He also breaks down Ephemeral Medical’s scaffold design, including its segmented architecture, balloon-expandable delivery system, bioresorbable polymer approach, and sirolimus coating.
The conversation also covers endothelialization, restenosis, first-in-human clinical progress, funding strategy, and what it takes to move a novel vascular platform from development toward IDE readiness and eventual US approval. For medtech professionals in vascular devices, stent and scaffold design, biomaterials, product development, and contract manufacturing, this episode is a detailed look at the future of bioresorbable technology in peripheral intervention.
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