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MedTech Unboxed: Presented by Chamfr

MedTech Unboxed: Presented by Chamfr

Business NewsMedicine54 episodes
MedTech Unboxed is Chamfr’s 20–40 minute podcast built specifically for MedTech R&D teams. Each episode brings together startup founders, visionary engineers, suppliers, and investors to unpack what’s next in materials, methods, and device technology. By connecting design decisions to funding realities and manufacturability, the show offers a cross-functional view of how great medical devices actually make it to market, giving engineers and innovators practical insight they can apply beyond the lab.
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Micro Metal Manufacturing in MedTech: Smaller Parts, Fewer Assembly Steps

Micro Metal Manufacturing in MedTech: Smaller Parts, Fewer Assembly Steps

24 min 10 sec
As MedTech devices get smaller, manufacturing gets more complicated. Tiny features can push teams toward multi-piece assemblies, added welding or bonding steps, tighter tolerance stacks, and costly design changes. In this episode of MedTech Unboxed, Adam Steege, Founder and CEO of Trio Labs, shares how Resin Infused Powder Lithography (RIPL) gives engineers a new way to produce small, complex metal components. Using an articulating device, he shows how thin walls can create more room for lumens, sensors, cables, and other functions within a small device profile. Adam also explains how textures, threads, welding features, and other details can be built directly into a component to reduce parts and simplify downstream assembly. It's a practical look at how a digital manufacturing process can make engineering changes less disruptive and how the technology can help teams move from early prototypes through volume production faster.
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Remote Heart Failure Monitoring: From Pressure to Multi-Parameter Insights

Remote Heart Failure Monitoring: From Pressure to Multi-Parameter Insights

21 min 50 sec
In 2026, heart failure still carries ~50% five-year mortality, and repeat hospitalizations remain a major burden for patients, families, and health systems. Remote monitoring is evolving to give care teams a more complete picture of what’s happening before patient conditions worsen. Laura Becerra-Fajardo, PhD, from FORESEE recently joined Steve to discuss the latest developments in remote heart failure monitoring and their approach to measuring multiple physiological parameters from a single pulmonary artery implant. The implant is powered and controlled by high-frequency current bursts applied through external electrodes. The body conducts the current to electrodes on the implant, so the device needs no battery and no coils. In this episode, she walks through the thinner capsule design, the 12 French delivery system, the five-minute at-home measurement, and the longer-term goal of physician-directed patient self-management. It’s an inside look at how FORESEE is combining multi-parameter sensing, miniaturization, and a familiar catheter-based workflow.
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Build the Business, Not Just the Product: MedTech Lessons from LSI Europe

Build the Business, Not Just the Product: MedTech Lessons from LSI Europe

33 min 49 sec
Strategics aren’t just looking for great MedTech products. They’re looking for de-risked businesses with a clear path to growth. In this episode of MedTech Unboxed, Steve talks with Omar Khateeb, Founder and CEO of MarketCraft, about his biggest takeaways from LSI Europe, a MedTech innovation and investment conference in Barcelona, and what they mean for founders, suppliers, and service partners. Omar shares what stood out from strategics including Stryker, Edwards, and CONMED, and why companies need to think about market de-risking alongside technical, clinical, and regulatory progress. He also discusses starting market development earlier and building a business that a potential acquirer can actually scale. For CDMOs and other MedTech professionals, the conversation also challenges the idea that conferences are primarily about immediate leads. Omar explains why understanding where technology and capital are moving, building relationships earlier, and creating familiarity before a prospect needs you can be far more valuable over time. It’s a practical look at what it takes to build a business around the technology.
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OrthodontiCell: Accelerating Orthodontic Treatment with Bioelectric Stimulation

OrthodontiCell: Accelerating Orthodontic Treatment with Bioelectric Stimulation

25 min 45 sec
Most people who have had braces or aligners remember the experience all too well: months or years of treatment, repeat office visits, discomfort, and retainers long after the teeth have moved. What if there were an innovative platform to change that? In this episode of MedTech Unboxed, Mark Terrill, CEO of OrthodontiCell, discusses how the company is applying bioelectric stimulation to address a familiar challenge: the time and burden involved in moving and stabilizing teeth. Mark walks through OrthodontiCell’s home-use platform, which delivers targeted bioelectric waveforms through a mouthpiece worn over braces or aligners. He explains the science behind the technology, the treatment-time and pain-reduction results the team has seen to date, and why the platform is being developed to address both tooth movement and post-treatment stability. This conversation also explores the innovation journey behind the platform, from published clinical research and electrical safety testing to OrthodontiCell’s regulatory pathway. It’s a compelling look at how a familiar unmet need, advanced technology, clinical evidence, and real-world workflow considerations can come together to create a new MedTech platform.
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EndoShunt: A 7 Fr Shunt for Abdominal Hemorrhage

EndoShunt: A 7 Fr Shunt for Abdominal Hemorrhage

25 min 30 sec
When a patient is bleeding in the abdomen, surgeons often face a bad tradeoff: control the hemorrhage by shutting off blood flow, or keep circulation going while they race to find and repair the injury. In this episode of MedTech Unboxed, Tyler Zanon, CEO of EndoShunt Medical, walks through a catheter-based shunt designed to control abdominal bleeding while maintaining distal flow. The team took the system from a 14 Fr concept to a low-profile 7 Fr device meant to fit existing trauma workflows. Tyler also covers preclinical testing, why they moved final device assembly to Resonetics, and the funding and teamwork required to push toward 510(k) and a clinical pilot.
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